Salvatore Pucciarelli

Full Professor

Telefono: + 39 3440682720

Phone lab: +39 0498212208


1994 Observer at the Surgery Department, Colorectal Service of the Memorial Sloan Kettering Cancer Center, NY, Usa.
1993 Two-month post-graduate course at the Surgical Unit (Director Prof. N.S.Williams) at The Royal London Hospital (University of London).
1988 Specialized in Gastroenterology and Digestive Endoscopy (marks 48/50) at the University of Padova, Italy
1986 Qualified as Head in General Surgery (marks 93/100)
1984 Specialized in General Surgery (marks 70/70 cum laude) at the University of Padova, Italy.
1978 Graduated in Medicine at University of Padova (marks 110/110)

From 1 October 2017 Director, Ist Surgical Unit, University of Padova
From 1 July 2017 Full Professor at the Dept. of Surgical, Oncological and Gastroenterological Sciences, University of Padova
1992 - 2017 Senior Assistant at the Institute "Clinica Chirurgica I", Azienda Ospedaliera - University of Padova.
2016 – 2017 Associate Professor in Surgery at the Dept. of Surgical, Oncological and Gastroenterological Sciences, University of Padova
1980- 2016 Permanent researcher at the Inst. "Clinica Chirurgica I", University of Padova
1978-1980 Resident physician, Department of Surgery, University of Padova

Colorectal cancer represents the main interest.
Standardization of diagnosis, staging, treatments, and follow up.
Institutional prospective colorectal online data base.
Responsible of Institutional Biobank.

Translational research:

- diagnostic and prognostic biological markers of colorectal cancer
- factors predictive of response to preoperative chemoradiotherapy (CRT) for rectal cancer
- genetic characterization of sporadic and familiar colorectal cancer

Clinical research:

- rectal cancer staging and re-staging after CRT
- organ preserving approach for rectal cancer after CRT
- surgical approach of rectal cancer to avoid anastomotic leakage (reconstruction technique, use of glue)
- surgical approach and management of hereditary colorectal cancer (FAP, A-FAP, HNPCC)
- quality of life and bowel function of colorectal cancer patients.

1. Maas, Monique; Nelemans, Patty J.; Valentini, Vincenzo; et al. Long-term outcome in patients with a pathological complete response after chemoradiation for rectal cancer: a pooled analysis of individual patient data. LANCET ONCOLOGY 2010;11:835-44

2. Guillem, Jose G.; Diaz-Gonzalez, Juan A.; Minsky, Bruce D.; et al. cT3N0 rectal cancer: Potential overtreatment with Preoperative chemoradiotherapy is warranted. JOURNAL OF CLINICAL ONCOLOGY. 2006;26:368-73

3. Aschele, C; Friso, ML; Pucciarelli, S; et al. A phase I-II study of weekly oxaliplatin, 5-fiuorouracil continuous infusion and preoperative radiotherapy in locally advanced rectal cancer. ANNALS OF ONCOLOGY 2005;16:1140-6

4. Maretto, Isacco; Pomerri, Fabio; Pucciarelli, Salvatore; et al. The potential of restaging in the prediction of pathologic response after preoperative chemoradiotherapy for rectal cancer. ANNALS OF SURGICAL ONCOLOGY. 2007;14:455-61

5. Pucciarelli, S; Capirci, C; Emanuele, U; et al. Relationship between pathologic T-stage and nodal metastasis after preoperative chemoradiotherapy for locally advanced rectal cancer. ANNALS OF SURGICAL ONCOLOGY. 2005;12:111-6

6. Rampazzo, E.; Bertorelle, R.; Serra, L.; et al. Relationship between telomere shortening, genetic instability, and site of tumour origin in colorectal cancers. BRITISH JOURNAL OF CANCER 2010;102:1300-5

7. Pucciarelli, Salvatore; Del Bianco, Paola; Efficace, Fabio; et al. Patient-Reported Outcomes After Neoadjuvant Chemoradiotherapy for Rectal Cancer A Multicenter Prospective Observational Study. ANNALS OF SURGERY. 2011; 253: 71-7

8. Vedovati, Maria Cristina; Becattini, Cecilia; Rondelli, Fabio; et al. A Randomized Study on 1-Week Versus 4-Week Prophylaxis for Venous Thromboembolism After Laparoscopic Surgery for Colorectal Cancer. ANNALS OF SURGERY. 2014;259:665-9

9. Fassan, Matteo; Pizzi, Marco; Giacomelli, Luciano; et al. PDCD4 nuclear loss inversely correlates with miR-21 levels in colon carcinogenesis. VIRCHOWS ARCHIV. 2011;458:413-9

10. Pomerri, Fabio; Pucciarelli, Salvatore; Maretto, Isacco; et al. Prospective assessment of imaging after preoperative chemoradiotherapy for rectal cancer. SURGERY. 2011;149:56-64

Funded by Institution: Ministero della Salute, Ricerca finalizzata. RF-2011-02349645
Year: 2012
Title: Early diagnosis, tumor response to neoadjuvant treatments and diagnosis of tumor recurrence using new and non-invasive biomarkers in colon and rectal cancer
Position: Principal Investigator

Funded by Institution: Università di Padova. Bando Progetto di Ateneo 2015. CPDA150821/15
Year: 2015
Title: Rectum preserving after preoperative radiochemotherapy
Position: Principal Investigator