Research

Urology

Overview of the research lines

- Group 1: kidney (focus- oncological and functional outcomes of nephron-sparing surgery for kidney cancers).
- Group 2: prostate cancer (focus- MRI and MRI/US fusion biopsy for prostate cancer).
- Group 3: bladder cancer (focus- recurrent bladder cancer after intravesical therapy and after radical cystectomy).
- Group 4: functional urology, Endourology and paediatric urology.

In the Urology Section, we are currently developing multiple research lines, covering broad aspects of the field of urology. The main focus of our Department is to improve the

•        Prostate cancer: role of active surveillance, role of mpMRI and fusion biopsy, PET/CT imaging of primary and recurrent cancer, outcomes of surgical treatment (robotic prostatectomy) and improvement of functional results of surgical treatment, high risk prostate cancer, metabolic syndrome and prostate cancer
•        Kidney cancer: surgical nephron-sparing treatment, robotic partial nephrectomy, surgical safety for robotic surgery, surgical management of vena cava thrombosis
•        Bladder cancer: intravesical therapy in non-muscle-invasive bladder cancer, outcome predictors for radical cystectomy in bladder cancer, recurrent bladder cancer after radical cystectomy
•        Functional urology: urodynamics, surgical treatment of male and female stress incontinence
•        Upper urothelial tract tumours and ureteral stenoses: endourologic management
•        Paediatric Urology.

5 selected references:

- Zattoni F, Morlacco A, Cattaneo F, Soligo M, Meggiato L, Modonutti D, Valotto C, Dal Moro F, Zattoni F. Development of a Surgical Safety Training Program and Checklist for Conversion during Robotic Partial Nephrectomies. Urology. 2017 Nov; 109:38-43. doi: 10.1016/j.urology.2017.06.057. Epub 2017 Aug 18.

- Antonelli A, Mari A, Longo N, Novara G, et al, Zattoni F. Role of Clinical and Surgical Factors for the Prediction of Immediate, Early and Late Functional Results, and its Relationship with Cardiovascular Outcome after Partial Nephrectomy: Results from the Prospective Multicenter RECORd 1 Project. J Urol. 2018 Apr; 199(4):927-932. doi: 10.1016/j.juro.2017.11.065. Epub 2017 Nov 14.

- Sharova E, Grassi A, Marcer A, Ruggero K, Pinto F, Bassi P, Zanovello P, Zattoni F, D'Agostino DM, Iafrate M, Ciminale V. A circulating miRNA assay as a first-line test for prostate cancer screening. Br J Cancer. 2016 Jun 14; 114(12):1362-6. doi: 10.1038/bjc.2016.151. Epub 2016 May 26.

- Evangelista L, Guttilla A, Zattoni F, Muzzio PC, Zattoni F. Utility of choline positron emission tomography/computed tomography for lymph node involvement identification in intermediate- to high-risk prostate cancer: a systematic literature review and meta-analysis. Eur Urol. 2013 Jun; 63(6):1040-8. doi: 10.1016/j.eururo.2012.09.039. Epub 2012 Sep 25. Review.

- Morlacco A, Sharma V, Viers BR, Rangel LJ, Carlson RE, Froemming A3, Karnes RJ. The Incremental Role of Magnetic Resonance Imaging for Prostate Cancer Staging before Radical Prostatectomy. Eur Urol. 2017 May; 71(5):701-704. doi: 10.1016/j.eururo.2016.08.015. Epub 2016 Aug 28.

People involved:

Filiberto Zattoni, Full Professor
Giacomo Novara, Associated Professor
Fabrizio Dal Moro, Associated Professor
Massimo Iafrate, Assistant Professo
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Marco Castagnetti, Associate Professo
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Group members

Prof. R. Jeffrey Karnes – Associate professor of Urology at Mayo Clinic in Rochester, MN - Dr. P. Beltrami – consultant at Urology Clinic -Dr. Dr. Fabio Zattoni, Dr. Alessandro Morlacco – PhD students -  Dr. Michele Colicchia, Dr. Matteo Soligo, Dr. Giovanni Motterle, Dr. Giovanni Costa, Dr. Zecchini – Urology residents.