Research

Liver transplantation

Main research interests

Organ allocation in liver transplantation (UC)
Induction immunosuppression in liver transplant candidates (UC)
Machine perfusion preservation in liver transplantation (UC, EG)
Paediatric liver transplantation, split liver, auxiliary and domino liver transplantation (UC, EG)
Transplant benefit (UC)
Downstaging treatment for cancer in liver transplant candidates (UC, EG, GZ)
Acute alcoholic hepatitis as indication for liver transplantation (PB)
HBV or HCV as indication for liver transplantation and prevention/treatment of recurrence after transplantation (PB and FPR)
Liver cancers as indication for liver transplantation and post-transplant follow-up (UC, PB and EG)
Metabolic Liver disease as indication for liver transplantation and de novo metabolic syndrome after transplantation (PB)
Adherence to medical treatments of transplant recipients (PB)
Quality of life of transplant recipients (PB)

 

Publications

Cillo U, Burra P, Mazzaferro V, Belli L, Pinna AD, Spada M, Nanni Costa A, Toniutto P; I-BELT (Italian Board of Experts in the Field of Liver Transplantation). A Multistep, Consensus-Based Approach to Organ Allocation in Liver Transplantation: Toward a "Blended Principle Model". Am J Transplant. 2015 Oct;15(10):2552-61.

Cillo U, Bechstein WO, Berlakovich G, Dutkowski P, Lehner F, Nadalin S, Saliba F, Schlitt HJ, Pratschke J. Identifying risk profiles in liver transplant candidates and implications for induction immunosuppression. Transplant Rev (Orlando). 2018 Jul;32(3):142-150

Vairetti M, Ferrigno A, Gringeri E, Cillo U. Representing Subnormothermic Machine Perfusion in Fatty Livers: The Complete Picture? Am J Transplant. 2017May;17(5):1421-1422. doi: 10.1111/ajt.14196. Epub 2017 Feb 14.

Burra P, Germani G, Adam R, Karam V, Marzano A, Lampertico P, Salizzoni M, Filipponi F, Klempnauer JL, Castaing D, Kilic M, Carlis LD, Neuhaus P, Yilmaz S, Paul A, Pinna AD,

Burroughs AK, Russo FP. Liver transplantation for HBV-related cirrhosis in Europe: an ELTR study on evolution and outcomes. J Hepatol. 2013 Feb;58(2):287-96.

Zanetto A, Shalaby S, Vitale A, Mescoli C, Ferrarese A, Gambato M, Franceschet E, Germani G, Senzolo M, Romano A, Angeli P, Rugge M, Farinati F, Forton DM, Cillo U, Burra P, Russo FP. Dropout rate from the liver transplant waiting list because of hepatocellular carcinoma progression in hepatitis C virus-infected patients treated with direct-acting antivirals. Liver Transpl. 2017 Sep;23(9):1103-1112

Burra P, Giannini EG, Caraceni P, Ginanni Corradini S, Rendina M, Volpes R, Toniutto P. Specific issues concerning the management of patients on the waiting list and after liver transplantation. Liver Int. 2018

Funding:

Ordinary department funding.

People involved:

Umberto Cillo (Full Professor)
Patrizia Burra, (Full Professor)
Enrico Gringeri (Associate Professor)
Giacomo Zanus (Associate Professor)
Francesco Paolo Russo (Associate Professor)

Group members: Domenico Bassi, Riccardo Boetto, Francesco D’Amico, Alessandro Vitale, Marina Polacco (Hepatobiliary Surgeons), Martina Gambato, Giacomo Germani and Marco Senzolo (consultant Hepatologists), Alessandra Bertacco, Michela Di Giunta (Hepatobiliary Surgery Fellows) Alberto Zanetto, Alberto Ferrarese, Chiara Becchetti, Salvatore Sciarrone and Sarah Shalaby (Gastroenterology Fellows).